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Research & evidence

Read a published clinical study and understand its design, relevance and limitations before discussing evidence with your clinician.

Man holding his chest in a heart-health awareness image

Read the evidence in context

Research can help frame questions about care. A published study is not a guarantee for an individual patient, proof that every component works, or confirmation that a protocol is available at this clinic.

PUBLISHED CLINICAL STUDY · 2017

Add-on therapy in chronic heart failure

Source title: Effect of heart failure reversal treatment as add-on therapy in patients with chronic heart failure: A randomized, open-label study

Authors: Rohit Sane, Abhijeet Aklujkar, Atul Patil and Rahul Mandole.
Journal: Indian Heart Journal, 69(3), 299–304 (2017).
DOI: 10.1016/j.ihj.2016.10.012.

The study evaluated a multimodal Ayurvedic procedure and allied therapies as an addition to standard chronic heart failure treatment. Its open-label design means participants and researchers knew the allocated treatment. Applicability depends on the patients, protocol and outcomes studied.

The paper’s use of “reversal” in its title should not be read as evidence that every coronary blockage reverses or that prescribed treatment can be stopped. Heart failure and coronary artery blockage are different clinical issues. Discuss the full paper and its limitations with your clinician.

Read the indexed study on PubMed

Connect evidence with your care

Check the original journal, study design, follow-up and conflicts of interest. Discuss what the evidence can and cannot tell you.

Heart health care

Questions to bring to your consultation

  • Were the participants similar to me?
  • Was the therapy studied alongside existing treatment?
  • Which outcomes were measured, and for how long?
  • What are the risks, uncertainties and alternatives?

Care should fit your situation

Educational information does not replace an individual medical consultation. Outcomes and suitability vary. Continue prescribed medicines unless your treating doctor changes them.